Monoclonal Antibody Charge Heterogeneity Analysis by Capillary Isoelectric Focusing on the Agilent 7100 Capillary Electrophoresis System
10 Jan 2013

Due to importance of monoclonal antibodies (mAb) as therapeutic agents, there is a growing demand for high resolution analytical methods to characterize these complex molecules. This application note describes the performance of the high resolution capillary isoelectric focusing (cIEF) method for mAb charge isoform analysis on the Agilent 7100 Capillary Electrophoresis (CE) system. The results of an intermediate precision study employing four different CE instruments are presented, with results showing that mAb charge heterogeneity analysis can be performed reliably and with high precision on the Agilent 7100 CE System.

Popular tags in SelectScience

Buying guides

Write a Review

Join the Global SelectScience Community Today! It’s FREE!

Helping you make informed decisions about the latest lab products and technologies:

  • Be the first to learn about new technologies
  • 10,000+ trusted product reviews from your peers
  • Compare 500,000 products and manufacturers
  • Get exclusive buying tips from experts
  • Find solutions fast: 10,000+ Application Notes, Webinars and Videos

Connect with 250,000 scientists... All in one place!

Become a member today!