Improving Quantification in Time of Flight (TOF) Mass Spectrometers by Optimizing Detector Response

21 May 2012

The aim of this application note is to improve quantification of ion abundance in a time of flight mass spectrometer by adjusting the operating parameters of the ion detector. The pulse amplitude distribution for a finite number of samples of a multi-ion peak with internal variation was measured for three different gain-balance settings of a hybrid ion detector.

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