Application Note: Human Nucleosome Map Highlights Best Epigenetic Markers
27 April 2012
Histone modifications regulate DNA transcription, repair, recombination, and replication, and can alter local chromatin architecture. The most commonly studied and best understood histone modifications are acetylation, phosphorylation, methylation, and ubiquitination. EMD Millipore offers over 200 validated antibodies, recombinant proteins, and kits to analyze histone modifications. This information-packed map of the human nucleosome is annotated with published histone modifications, as well as with available research reagents for histone modification and epigenetics research.