Application Note: CAR-T Cell Screening in Tumor Spheroids using Corning® Spheroid Microplates
26 May 2017

Chimeric antigen receptor (CAR)-T cells, which are engineered to recognize target cell surface antigens expressed on tumor cells, have shown promise to effect complete remission in patients with B-cell malignancies. In combination with KILR Cytotoxicity Assays and ProMab CAR-T cells, the Corning spheroid microplate provides a high throughput platform for culturing and screening tumor spheroids with CAR-T cell assays.