An Automated, Cell-based Platform for the Rapid Detection of Novel Androgen Receptor Modulators
19 Nov 2012

An automated high throughput screening approach to identify novel modulators of Androgen Receptor (AR) activity is demonstrated in this application note from BioTek. The study incorporated a new whole-cell, luciferase-based assay to quantify human AR activity. Chemicals identified in the primary screen as putative AR inhibitors were further analyzed using a live cell multiplex assay. Results demonstrate how the combination of the novel, cell-based chemistries and automation can be used to rapidly, and accurately identify modulators of this important drug target.

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