CyFlow™ CD15 Pacific Orange™

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Product Details

Manufacturer
Cat. No.
AS196272
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

CD15 (Le(x); Lewis x or SSEA-1; stage specific embryonic antigen-1) is a trisacharide determinant (3-fucosyl-N-acetyllactosamine) expressed on several glycolipids, glycoproteins and proteoglycans of various cell types, e.g. granulocytes, mast cells, monocytes, macrophages, cells of gastric mucosa, nervous system or various tumor cells. There are several variants of Lewis x, such as sialyl-Lewis x or sulphated Lewis x. Cells with high surface expression of Le(x) antigen exhibit strong self-aggregation, based on calcium-dependent Le(x)-Le(x) interaction. This process is involved for example in embryo compaction or in autoaggregation of teratocarcinoma cells. Sialyl-Le(x) and its isomer sialyl-Le(a) are ligands of selectins. CD15 expression has been extensively used to confirm diagnosis of Hodgkin´s disease.

Alternative Names

Lewis X

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Human
Antigen CD15
Conjugate Pacific Orange™
Isotype IgM

Handling

Quantity 100 tests
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in stabilizing Tris buffered saline (TBS) solution, pH ≈8.0, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Immunoprecipitation (IP)

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CyFlow™ CD15 Pacific Orange™


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Manufacturer:
Catalogue Number:
AS196272
Antibody Type
Primary Antibody