CyFlow™ CD14 PerCP-Cy5.5

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Product Details

Manufacturer
Cat. No.
CL770609
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

CD14 is a 55 kDa GPI-anchored glycoprotein, constitutively expressed on the surface of mature monocytes, macrophages, and neutrophils, where serves as a multifunctional lipopolysaccharide receptor; it is also released to the serum both as a secreted and enzymatically cleaved GPI-anchored form. CD14 binds lipopolysaccharide molecule in a reaction catalyzed by lipopolysaccharide-binding protein (LBP), an acute phase serum protein. The soluble sCD14 is able to discriminate slight structural differences between lipopolysaccharides and is important for neutralization of serum allochthonous lipopolysaccharides by reconstituted lipoprotein particles. CD14 affects allergic, inflammatory and infectious processes.

Alternative Names

LPS-R

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Human, Non-Human Primate
Antigen CD14
Conjugate PerCP-Cy5.5
Isotype IgG1

Handling

Quantity 100 tests
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Immunoprecipitation (IP)

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CyFlow™ CD14 PerCP-Cy5.5


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Manufacturer:
Catalogue Number:
CL770609
Antibody Type
Primary Antibody