CyFlow™ CD11b Purified

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Product Details

Manufacturer
Cat. No.
BE254681
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

CD11b (integrin αM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with CD18 (integrin β2 subunit); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.

Alternative Names

Mac-1

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Human
Antigen CD11b
Conjugate Purified
Isotype IgG2a

Handling

Quantity 0.1 mg
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Immunoprecipitation (IP)

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CyFlow™ CD11b Purified


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Manufacturer:
Catalogue Number:
BE254681
Antibody Type
Primary Antibody