CyFlow™ CD11b APC

Be the first to review this product

Product Details

Manufacturer
Cat. No.
BR751578
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat

Buy Now

Place your order directly with the manufacturer.

Description

CD11b (integrin αM subunit) is a 165-170 kDa type I transmembrane glycoprotein that non-covalently associates with CD18 (integrin β2 subunit); expression of the CD11b chain on the cell surface requires the presence of the CD18 antigen. CD11b/CD18 integrin (Mac-1, CR3) is highly expressed on NK cells, neutrophils, monocytes and less on macrophages. CD11b/CD18 integrin is implicated in various adhesive interactions of monocytes, macrophages and granulocytes, facilitating their diapedesis, as well as it mediates the uptake of complement coated particles, serving as a receptor for the iC3b fragment of the third complement component.

Alternative Names

Mac-1

Biological Information

Clonality Monoclonal
Host Rat
Reactivity Human, Mouse, Non-Human Primate, Rabbit (Lapine)
Antigen CD11b
Conjugate APC
Isotype IgG2b

Handling

Quantity 0.1 mg
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Functional Studies (Func), Immunohistochemistry (Formalin-Fixed Sections) (IHC (F)), Immunoprecipitation (IP)

0 Scientists have reviewed this product


Write the First Review

No Reviews

Antibody Overview

Product Image

CyFlow™ CD11b APC


Be the first to review this product

Manufacturer:
Catalogue Number:
BR751578
Antibody Type
Primary Antibody