CyFlow™ CD8a Low Endotoxin

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Product Details

Cat. No.
Primary Antibody

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The CD8a (CD8 α) subunit of CD8 T cell coreceptor is expressed in CD8 α/β heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 α/α homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 α/β but not α/α dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.

Alternative Names

T8, Leu2

Biological Information

Clonality Monoclonal
Host Rat
Reactivity Mouse
Antigen CD8a
Conjugate Low Endotoxin
Isotype IgG2a


Quantity 0.1 mg
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.


Flow Cytometry (FC), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)

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CyFlow™ CD8a Low Endotoxin

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Catalogue Number:
Antibody Type
Primary Antibody