CyFlow™ CD8a Alexa Fluor™ 488

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Product Details

Cat. No.
Primary Antibody

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The CD8a (CD8 α) subunit of CD8 T cell coreceptor is expressed in CD8 α/β heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 α/α homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages and dendritic cells. Regulation of CD8 beta level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 α/β but not α/α dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.

Alternative Names

T8, Leu2

Biological Information

Clonality Monoclonal
Host Rat
Reactivity Mouse
Antigen CD8a
Conjugate Alexa Fluor™ 488
Isotype IgG2a


Quantity 0.1 mg
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.


Flow Cytometry (FC), Functional Studies (Func), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunoprecipitation (IP)

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CyFlow™ CD8a Alexa Fluor™ 488

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Catalogue Number:
Antibody Type
Primary Antibody