CyFlow™ CD8 PE-Cy7

Be the first to review this product

Product Details

Manufacturer
Cat. No.
BA413066
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

Buy Now

Place your order directly with the manufacturer.

Description

The CD8 T cell coreceptor (monomer approx. 32-34 kDa) is expressed as α/β heterodimer on majority of MHC I-restricted conventional T cells and thymocytes and as α/α homodimer on subsets of memory T cells, intraepithelial lymphocytes, NK cells and dendritic cells. Regulation of CD8 β level on T cell surface seems to be an important mechanism to control their effector function. Assembly of CD8 α-β but not α-α dimers is connected with formation or localization to the lipid rafts. Recruiting triggered TCR complexes to these membrane microdomains as well as affinity of TCR to MHC I is modulated by CD8, thereby affecting the functional diversity of the TCR signaling.

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Human
Antigen CD8
Conjugate PE-Cy7
Isotype IgG2a

Handling

Quantity 100 tests
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Immunoprecipitation (IP)

0 Scientists have reviewed this product


Write the First Review

No Reviews

Antibody Overview

Product Image

CyFlow™ CD8 PE-Cy7


Be the first to review this product

Manufacturer:
Catalogue Number:
BA413066
Antibody Type
Primary Antibody