CyFlow™ CD7 PE-Cy5

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Product Details

Manufacturer
Cat. No.
CE144338
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

CD7 (gp40) is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.

Alternative Names

gp40

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Human
Antigen CD7
Conjugate PE-Cy5
Isotype IgG1

Handling

Quantity 100 tests
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P)), Immunoprecipitation (IP), Western Blotting (WB)

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CyFlow™ CD7 PE-Cy5


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Manufacturer:
Catalogue Number:
CE144338
Antibody Type
Primary Antibody