CyFlow™ CD6 Purified

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Product Details

Manufacturer
Cat. No.
CK650945
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

CD6 (T12) is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166 (ALCAM; activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells.

Alternative Names

T12

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Human
Antigen CD6
Conjugate Purified
Isotype IgG1

Handling

Quantity 0.1 mg
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Immunohistochemistry (Paraffin-Embedded Sections) (IHC (P)), Immunoprecipitation (IP), Western Blotting (WB)

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CyFlow™ CD6 Purified


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Manufacturer:
Catalogue Number:
CK650945
Antibody Type
Primary Antibody