CyFlow™ CD2 Purified

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Product Details

Manufacturer
Cat. No.
BU366628
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

CD2 (LFA-2) belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.

Alternative Names

LFA-2

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Human
Antigen CD2
Conjugate Purified
Isotype IgG1

Handling

Quantity 0.1 mg
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Immunoprecipitation (IP)

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CyFlow™ CD2 Purified


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Manufacturer:
Catalogue Number:
BU366628
Antibody Type
Primary Antibody