CyFlow™ CD2 Pacific Blue™

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Product Details

Manufacturer
Cat. No.
CX149909
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse

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Description

CD2 (LFA-2) belongs to T lymphocyte glycoproteins of immunoglobulin superfamily. Its interaction with CD58 stabilizes adhesion between T cells and antigen presenting or target cells. Relatively low affinity of CD2 to CD58 (as measured in solution) is compensated within the two-dimensional cell-cell interface to provide tight adhesion. Moreover, T cell activation induces increased CD2 expression and its lateral mobility, making easier contact between CD2 and CD58. Subsequently, T cell activation causes fixation of CD58-CD2 at sites of cell-cell contact, thereby strengthening intercellular adhesion. CD2 deficiency reduces intestinal inflammation and helps to control infection.

Alternative Names

LFA-2

Biological Information

Clonality Monoclonal
Host Mouse
Reactivity Human
Antigen CD2
Conjugate Pacific Blue™
Isotype IgG2b

Handling

Quantity 100 tests
Format liquid
Storage Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
Buffer The reagent is provided in stabilizing phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.1% (w/v) sodium azide.

Applications

Flow Cytometry (FC), Immunoprecipitation (IP)

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CyFlow™ CD2 Pacific Blue™


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Manufacturer:
Catalogue Number:
CX149909
Antibody Type
Primary Antibody