In this video, Wolfgang Hempell discusses ‘The Open Source Microscopy Concept’ showcasing the flexible IX3 inverted microscope frame series. This series provides solutions by enabling a customizable hardware set-up. The new open source frame concept has been designed around an infinite light path made easily accessible with interchangeable optical modules that can be swapped in and out of the light path, enabling the creation of various distinct systems on one inverted microscope frame. In addition, Wolfgang demonstrates the cellVivo system, a modular and flexible ‘one size fits all’ incubation system, which is fully adaptable for basic and high-end inverted microscopes. Interview filmed by SelectScience at analytica 2014.